Metadata

Name CCU002_01 Thrombocytopenia
Type Disease or Syndrome
Group Disease or Syndrome
Data Sources








Clinical Terminologies SNOMED-CT
ICD-10
Read version 2
Codelists covid_impact_ccu00201_thrombocytopenia_England_ICD10.csv covid_impact_ccu00201_TCP_covariate_only_England_SNOMEDCT.csv covid_impact_ccu00201_TCP_Wales_Read2.csv
Valid Event Data Range 01/01/1997 - 07/12/2020
Sex Female
Male
Authors Rochelle Knight, Venexia Walker, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Rachel Denholm, Ashley Akbari, Hoda Abbasizanjani, Fatemeh Torabi, Efosa Omigie, Sam Hollings, Teri-Louise North, Renin Toms, Emanuele Di Angelantonio, Spiros Denaxas,, Johan H Thygesen, Christopher Tomlinson, Ben Bray, Craig J Smith, Mark Barber, George Davey Smith, Nishi Chaturvedi, Cathie Sudlow, William N Whiteley, Angela Wood, Jonathan A C Sterne,, CVD-COVID-UK/COVID-IMPACT consortium, Longitudinal Health and Wellbeing COVID-19 National Core Study
Agreement Date 24 Nov 2021
Version (UUID) Revision 1 (COVID-IMPACT)

Phenotypes

England hospitalization EHR: Thrombocytopenia diagnosis

terminology code term code_type
ICD10 D69.6 Thrombocytopenia 1
ICD10 D69.5 Thrombocytopenia 1
ICD10 D69.4 Thrombocytopenia 1
ICD10 D69.3 Thrombocytopenia 1

England primary care EHR: Thrombocytopenia (as covariate) diagnosis

terminology code term code_type
SNOMEDCT 402653004 Thrombocytopenic purpura due to defective platelet production 1
SNOMEDCT 783251006 Hereditary thrombocytopenia with normal platelets 1
SNOMEDCT 866152006 Thrombocytopenia due to 2019 novel coronavirus 1
SNOMEDCT 33183004 Post infectious thrombocytopenic purpura 1
SNOMEDCT 438492008 Hereditary thrombocytopenic disorder 1
SNOMEDCT 441511006 History of immune thrombocytopenia 1
SNOMEDCT 73397007 Heparin induced thrombocytopaenia 1
SNOMEDCT 74576004 Acquired thrombocytopenia 1
SNOMEDCT 2897005 Immune thrombocytopenia 1
SNOMEDCT 371106008 Idiopathic maternal thrombocytopenia 1
SNOMEDCT 32273002 Idiopathic thrombocytopenic purpura 1
SNOMEDCT 13172003 Autoimmune thrombocytopenic purpura 1
SNOMEDCT 49341000119108 History of thrombocytopaenia 1
SNOMEDCT 191322006 Thrombocytopenia caused by drugs 1
SNOMEDCT 78129009 Thrombotic thrombocytopenic purpura 1
SNOMEDCT 154826009 Secondary thrombocytopenia 1
SNOMEDCT 417626001 Thrombocytopenic purpura associated with metabolic disorder 1
SNOMEDCT 726769004 HIT (Heparin induced thrombocytopenia) antibody 1
SNOMEDCT 87902006 Thrombocytopenia due to non-immune destruction 1
SNOMEDCT 32273002 Immune thrombocytopenic purpura 1
SNOMEDCT 267534000 Primary thrombocytopenia 1
SNOMEDCT 191323001 Thrombocytopenia due to extracorporeal circulation of blood 1
SNOMEDCT 78345002 Thrombocytopenia due to diminished platelet production 1
SNOMEDCT 441322009 Drug induced thrombotic thrombocytopenic purpura 1
SNOMEDCT 438476003 Autoimmune thrombotic thrombocytopenic purpura 1
SNOMEDCT 439007008 Acquired thrombotic thrombocytopenic purpura 1
SNOMEDCT 28505005 Acute idiopathic thrombocytopenic purpura 1
SNOMEDCT 82190001 Thrombocytopenia due to defective platelet production 1
SNOMEDCT 402654005 Thrombocytopenic purpura due to platelet consumption 1
SNOMEDCT 36070007 Immunodeficiency with thrombocytopenia AND eczema 1
SNOMEDCT 111588002 Heparin associated thrombotic thrombocytopenia 1
SNOMEDCT 19307009 Drug-induced immune thrombocytopenia 1
SNOMEDCT 128091003 Autoimmune thrombocytopenia 1
SNOMEDCT 302873008 Thrombocytopenic purpura 1

Wales primary care EHR: Thrombocytopenia diagnosis

Phenotype Read code Description Category
TCP 42P2. Auto-immune thrombocytopenia Primary or Idiopathic Thrombocytopaenia
TCP 42P2. Thrombocytopenia Secondary or other Thrombocytopaenia
TCP 42P8. Heparin induced thrombocytopenia screening test Secondary or other Thrombocytopaenia
TCP C3912 Wiskott - Aldrich syndrome Secondary or other Thrombocytopaenia
TCP D313. Primary thrombocytopenia Primary or Idiopathic Thrombocytopaenia
TCP D3130 Idiopathic thrombocytopenic purpura Primary or Idiopathic Thrombocytopaenia
TCP D3131 Congenital thrombocytopenic purpura Primary or Idiopathic Thrombocytopaenia
TCP D3133 [X]Essential thrombocytopenia NOS Primary or Idiopathic Thrombocytopaenia
TCP D313y Other specified primary thrombocytopenia Primary or Idiopathic Thrombocytopaenia
TCP D313z Primary thrombocytopenia NOS Primary or Idiopathic Thrombocytopaenia
TCP D314. Secondary thrombocytopenia Secondary or other Thrombocytopaenia
TCP D3141 Thrombocytopenia due to drugs Secondary or other Thrombocytopaenia
TCP D3142 Thrombocytopenia due to extracorporeal circulation of blood Secondary or other Thrombocytopaenia
TCP D3143 Heparin-induced thrombocytopenia Secondary or other Thrombocytopaenia
TCP D314y Other specified secondary thrombocytopenia Secondary or other Thrombocytopaenia
TCP D314z Secondary thrombocytopenia NOS Secondary or other Thrombocytopaenia
TCP D315. Thrombocytopenia NOS Secondary or other Thrombocytopaenia
TCP Dyu32 [X]Other primary thrombocytopenia Primary or Idiopathic Thrombocytopaenia
TCP G7561 Thrombotic thrombocytopenic purpura Secondary or other Thrombocytopaenia

Publication

Rochelle Knight, Venexia Walker, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Rachel Denholm, Ashley Akbari, Hoda Abbasizanjani, Fatemeh Torabi, Efosa Omigie, Sam Hollings, Teri-Louise North, Renin Toms, Emanuele Di Angelantonio, Spiros Denaxas, Johan H Thygesen, Christopher Tomlinson, Ben Bray, Craig J Smith, Mark Barber, George Davey Smith, Nishi Chaturvedi, Cathie Sudlow, William N Whiteley, Angela Wood, Jonathan A C Sterne, for the CVD-COVID-UK/COVID-IMPACT consortium and the Longitudinal Health and Wellbeing COVID-19 National Core Study. Association of COVID-19 with arterial and venous vascular diseases: a population-wide cohort study of 48 million adults in England and Wales

medRxiv 2021.11.22.21266512; doi: https://doi.org/10.1101/2021.11.22.21266512