Metadata

Name CCU002_01 Thrombophilia
Type Disease or Syndrome
Group Disease or Syndrome
Data Sources








Clinical Terminologies SNOMED-CT
ICD-10
Read version 2
Codelists covid_impact_ccu00201_thrombophilia_England_SNOMEDCT.csv covid_impact_ccu00201_thrombophilia_England_ICD10.csv covid_impact_ccu00201_THROMBOPHILIA_Wales_Read2.csv
Valid Event Data Range 01/01/1997 - 07/12/2020
Sex Female
Male
Authors Rochelle Knight, Venexia Walker, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Rachel Denholm, Ashley Akbari, Hoda Abbasizanjani, Fatemeh Torabi, Efosa Omigie, Sam Hollings, Teri-Louise North, Renin Toms, Emanuele Di Angelantonio, Spiros Denaxas,, Johan H Thygesen, Christopher Tomlinson, Ben Bray, Craig J Smith, Mark Barber, George Davey Smith, Nishi Chaturvedi, Cathie Sudlow, William N Whiteley, Angela Wood, Jonathan A C Sterne,, CVD-COVID-UK/COVID-IMPACT consortium, Longitudinal Health and Wellbeing COVID-19 National Core Study
Agreement Date 24 Nov 2021
Version (UUID) Revision 1 (COVID-IMPACT)

Phenotypes

England primary care EHR: Thrombophilia

terminology code term code_type
SNOMEDCT 442760001 Thrombophilia caused by antineoplastic agent therapy 1
SNOMEDCT 441697004 Thrombophilia associated with pregnancy 1
SNOMEDCT 442078001 Thrombophilia due to malignant neoplasm 1
SNOMEDCT 442121006 Thrombophilia due to vascular anomaly 1
SNOMEDCT 441762006 Thrombophilia due to immobilisation 1
SNOMEDCT 439002002 Thrombophilia due to acquired protein C deficiency 1
SNOMEDCT 441946009 Thrombophilia due to myeloproliferative disorder 1
SNOMEDCT 441079006 Thrombophilia due to antiphospholipid antibody 1
SNOMEDCT 439001009 Acquired thrombophilia 1
SNOMEDCT 439698008 Primary thrombophilia 1
SNOMEDCT 439698008 Hereditary thrombophilia 1
SNOMEDCT 441882000 History of thrombophilia 1
SNOMEDCT 234467004 Thrombophilia 1
SNOMEDCT 439126002 Thrombophilia due to acquired antithrombin III deficiency 1
SNOMEDCT 439125003 Thrombophilia due to acquired protein S deficiency 1
SNOMEDCT 441990004 Thrombophilia due to paroxysmal nocturnal haemoglobinuria 1
SNOMEDCT 442363001 Thrombophilia caused by vascular device 1
SNOMEDCT 442654007 Thrombophilia caused by hormone therapy 1
SNOMEDCT 442197003 Thrombophilia caused by drug therapy 1
SNOMEDCT 441945008 Thrombophilia due to trauma 1
SNOMEDCT 783250007 Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency 1

England hospitalization EHR: Thrombophilia

terminology code term code_type
ICD10 D68.5 Primary thrombophilia 1
ICD10 D68.6 Other thrombophilia 1

Wales primary care EHR: Thrombophilia

Phenotype Read code Description Category
THROMBOPHILIA 42Qc. Plasma activated protein C resistance Diagnosis of Thrombophilia
THROMBOPHILIA 42Qe. Factor V Leiden genotype Diagnosis of Thrombophilia
THROMBOPHILIA 42jH. Activated protein C with factor V deficient plasma Diagnosis of Thrombophilia
THROMBOPHILIA 43GE1 Lupus anticoagulant positive Diagnosis of Thrombophilia
THROMBOPHILIA D3037 Factor V Leiden mutation Diagnosis of Thrombophilia
THROMBOPHILIA D3038 Homozygous factor V Leiden mutation Diagnosis of Thrombophilia
THROMBOPHILIA D3039 Heterozygous factor V Leiden mutation Diagnosis of Thrombophilia
THROMBOPHILIA D309. Protein S deficiency Diagnosis of Thrombophilia
THROMBOPHILIA D30A. Thrombophilia Diagnosis of Thrombophilia
THROMBOPHILIA D30A0 Primary thrombophilia Diagnosis of Thrombophilia
THROMBOPHILIA D30B. Protein C deficiency Diagnosis of Thrombophilia
THROMBOPHILIA N006. Antiphospholipid syndrome Diagnosis of Thrombophilia

Publication

Rochelle Knight, Venexia Walker, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Rachel Denholm, Ashley Akbari, Hoda Abbasizanjani, Fatemeh Torabi, Efosa Omigie, Sam Hollings, Teri-Louise North, Renin Toms, Emanuele Di Angelantonio, Spiros Denaxas, Johan H Thygesen, Christopher Tomlinson, Ben Bray, Craig J Smith, Mark Barber, George Davey Smith, Nishi Chaturvedi, Cathie Sudlow, William N Whiteley, Angela Wood, Jonathan A C Sterne, for the CVD-COVID-UK/COVID-IMPACT consortium and the Longitudinal Health and Wellbeing COVID-19 National Core Study. Association of COVID-19 with arterial and venous vascular diseases: a population-wide cohort study of 48 million adults in England and Wales

medRxiv 2021.11.22.21266512; doi: https://doi.org/10.1101/2021.11.22.21266512