Metadata

Name CCU002_02 Stroke
Type Disease or Syndrome
Group Disease or Syndrome
Data Sources




Clinical Terminologies SNOMED-CT
ICD-10
Codelists covid_impact_ccu00202_stroke_HS_England_ICD10.csv covid_impact_ccu00202_stroke_HS_England_SNOMEDCT.csv covid_impact_ccu00202_stroke_IS_England_SNOMEDCT.csv covid_impact_ccu00202_stroke_IS_England_ICD10.csv covid_impact_ccu00202_stroke_NOS_England_SNOMEDCT.csv covid_impact_ccu00202_stroke_NOS_England_ICD10.csv covid_impact_ccu00202_stroke_SAH_England_ICD10.csv covid_impact_ccu00202_stroke_TIA_England_SNOMEDCT.csv covid_impact_ccu00202_stroke_TIA_England_ICD10.csv
Valid Event Data Range 08/12/2020 - 18/03/2021
Sex Female
Male
Authors CVD-COVID-UK consortium, William N Whiteley, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Venexia Walker, Rachel Denholm, Ashley Akbari, Efosa Omigie, Sam Hollings, Emanuele Di Angelantonio, Spiros Denaxas, Angela Wood, Jonathan A C Sterne, Cathie Sudlow
Agreement Date 23 Aug 2021
Version (UUID) Revision 1 (COVID-IMPACT)

Phenotypes

Code type is set to 1 for incident events, and 0 for prevalent events.

England hospitalization EHR: Haemorrhagic stroke

terminology code term code_type
ICD10 I61 Nontraumatic intracerebral hemorrhage 1.0
ICD10 I61 Nontraumatic intracerebral hemorrhage 1.0

England primary care EHR: Haemorrhagic stroke

terminology code term code_type
SNOMEDCT 7713009 Intrapontine hemorrhage 1.0
SNOMEDCT 49422009 Cortical hemorrhage 1.0
SNOMEDCT 52201006 Internal capsule hemorrhage 1.0
SNOMEDCT 75038005 Cerebellar hemorrhage 1.0
SNOMEDCT 195165005 Basal ganglia hemorrhage 1.0
SNOMEDCT 195167002 External capsule hemorrhage 1.0
SNOMEDCT 195168007 Intracerebral haemorrhage, intraventricular 1.0
SNOMEDCT 195169004 Intracerebral hemorrhage, multiple localized 1.0
SNOMEDCT 230710000 Lobar cerebral hemorrhage 1.0
SNOMEDCT 274100004 Cerebral hemorrhage 1.0
SNOMEDCT 308128006 Right sided intracerebral hemorrhage, unspecified 1.0
SNOMEDCT 732923001 Hemorrhage of medulla oblongata (disorder) 1.0
SNOMEDCT 230712008 Lacunar hemorrhage (disorder) 1.0
SNOMEDCT 276722003 Intracerebellar and posterior fossa hemorrhage (disorder) 1.0
SNOMEDCT 95454007 Brain stem hemorrhage (disorder) 1.0
SNOMEDCT 1078001000000105 Haemorrhagic stroke (disorder) 1.0
SNOMEDCT 20908003 Subcortical cerebral hemorrhage (disorder) 1.0
SNOMEDCT 230709005 Massive supratentorial cerebral hemorrhage (disorder) 1.0
SNOMEDCT 230711001 Thalamic hemorrhage (disorder) 1.0

England primary care EHR: Ischaemic stroke

terminology code term code_type
SNOMEDCT 230704000 Multi-infarct state (disorder) 1.0
SNOMEDCT 230692004 Infarction - precerebral 1.0
SNOMEDCT 230698000 Lacunar infarction 1.0
SNOMEDCT 71444005 Cerebral thrombosis 1.0
SNOMEDCT 75543006 Cerebral embolism 1.0
SNOMEDCT 78569004 Posterior inferior cerebellar artery syndrome 1.0
SNOMEDCT 95457000 Brain stem infarction 1.0
SNOMEDCT 95460007 Cerebellar infarction 1.0
SNOMEDCT 195185009 Cerebral infarct due to thrombosis of precerebral arteries 1.0
SNOMEDCT 195186005 Cerebral infarction due to embolism of precerebral arteries 1.0
SNOMEDCT 195189003 Cerebral infarction due to thrombosis of cerebral arteries 1.0
SNOMEDCT 195190007 Cerebral infarction due to embolism of cerebral arteries 1.0
SNOMEDCT 195200006 Carotid artery syndrome hemispheric 1.0
SNOMEDCT 195201005 Multiple and bilateral precerebral artery syndromes 1.0
SNOMEDCT 195209007 Middle cerebral artery syndrome 1.0
SNOMEDCT 195210002 Anterior cerebral artery syndrome 1.0
SNOMEDCT 195211003 Posterior cerebral artery syndrome 1.0
SNOMEDCT 230691006 CVA - cerebrovascular accident due to cerebral artery occlusion 1.0
SNOMEDCT 230692004 Infarction - precerebral 1.0
SNOMEDCT 230698000 Lacunar infarction 1.0
SNOMEDCT 230699008 Pure motor lacunar syndrome 1.0
SNOMEDCT 230700009 Pure sensory lacunar infarction 1.0
SNOMEDCT 307766002 Left sided cerebral infarction 1.0
SNOMEDCT 307767006 Right sided cerebral infarction 1.0
SNOMEDCT 373606000 Occlusive stroke (disorder) 1.0
SNOMEDCT 413102000 Infarction of basal ganglia (disorder) 1.0
SNOMEDCT 432504007 Cerebral infarction (disorder) 1.0
SNOMEDCT 724424009 Cerebral ischemic stroke due to small artery occlusion (disorder) 1.0
SNOMEDCT 125081000119106 Cerebral infarction due to occlusion of precerebral artery 1.0
SNOMEDCT 140921000119102 Ischaemic stroke without coma 1.0
SNOMEDCT 1089421000000105 Cerebral infarction due to stenosis of cerebral artery (disorder) 1.0
SNOMEDCT 16000511000119103 Cerebrovascular accident due to occlusion of left middle cerebral artery (disorder) 1.0
SNOMEDCT 16002031000119102 Cerebrovascular accident due to thrombus of right middle cerebral artery (disorder) 1.0
SNOMEDCT 16002111000119106 Cerebrovascular accident due to thrombus of left middle cerebral artery (disorder) 1.0
SNOMEDCT 195230003 Cerebral infarction due to cerebral venous thrombosis, non-pyogenic (disorder) 1.0
SNOMEDCT 20059004 Occlusion of cerebral artery (disorder) 1.0
SNOMEDCT 230693009 Anterior cerebral circulation infarction (disorder) 1.0
SNOMEDCT 230696001 Posterior cerebral circulation infarction (disorder) 1.0
SNOMEDCT 230701008 Pure sensorimotor lacunar infarction (disorder) 1.0
SNOMEDCT 307363008 Multiple lacunar infarcts (disorder) 1.0
SNOMEDCT 329641000119104 Cerebrovascular accident due to thrombus of basilar artery (disorder) 1.0
SNOMEDCT 371041009 Embolic stroke (disorder) 1.0
SNOMEDCT 734383005 Thrombosis of left middle cerebral artery (disorder) 1.0
SNOMEDCT 87555007 Claude's syndrome (disorder) 1.0
SNOMEDCT 1089411000000104 Cerebral infarction due to occlusion of cerebral artery (disorder) 1.0
SNOMEDCT 195213000 Cerebellar stroke syndrome (disorder) 1.0
SNOMEDCT 230694003 Total anterior cerebral circulation infarction (disorder) 1.0
SNOMEDCT 230695002 Partial anterior cerebral circulation infarction (disorder) 1.0
SNOMEDCT 230702001 Lacunar ataxic hemiparesis (disorder) 1.0
SNOMEDCT 230703006 Dysarthria-clumsy hand syndrome (disorder) 1.0
SNOMEDCT 230704000 Multi-infarct state (disorder) 1.0
SNOMEDCT 24654003 Weber-Gubler syndrome (disorder) 1.0
SNOMEDCT 25133001 Completed stroke (disorder) 1.0
SNOMEDCT 276219001 Occipital cerebral infarction (disorder) 1.0
SNOMEDCT 276220007 Foville syndrome (disorder) 1.0
SNOMEDCT 276221006 Millard-Gubler syndrome (disorder) 1.0
SNOMEDCT 276222004 Top of basilar syndrome (disorder) 1.0
SNOMEDCT 413758000 Cardioembolic stroke (disorder) 1.0
SNOMEDCT 426107000 Acute lacunar infarction (disorder) 1.0
SNOMEDCT 734384004 Thrombosis of right middle cerebral artery (disorder) 1.0
SNOMEDCT 90099008 Subcortical leukoencephalopathy (disorder) 1.0
SNOMEDCT 16002111000119100 Cerebrovascular accident due to thrombus of left middle cerebral artery (disorder) 1.0
SNOMEDCT 195230003 Cerebral infarction due to cerebral venous thrombosis, non-pyogenic (disorder) 1.0
SNOMEDCT 87555007 Claude's syndrome (disorder) 1.0
SNOMEDCT 1089411000000100 Cerebral infarction due to occlusion of cerebral artery (disorder) 1.0
SNOMEDCT 195210002 Anterior cerebral artery syndrome 1.0
SNOMEDCT 230699008 Pure motor lacunar syndrome 1.0
SNOMEDCT 230694003 Total anterior cerebral circulation infarction (disorder) 1.0
SNOMEDCT 230695002 Partial anterior cerebral circulation infarction (disorder) 1.0
SNOMEDCT 20059004 Occlusion of cerebral artery (disorder) 1.0
SNOMEDCT 413102000 Infarction of basal ganglia (disorder) 1.0
SNOMEDCT 307767006 Right sided cerebral infarction 1.0
SNOMEDCT 373606000 Occlusive stroke (disorder) 1.0
SNOMEDCT 195189003 Cerebral infarction due to thrombosis of cerebral arteries 1.0
SNOMEDCT 432504007 Cerebral infarction (disorder) 1.0
SNOMEDCT 724424009 Cerebral ischemic stroke due to small artery occlusion (disorder) 1.0
SNOMEDCT 95457000 Brain stem infarction 1.0
SNOMEDCT 95460007 Cerebellar infarction 1.0
SNOMEDCT 329641000119104 Cerebrovascular accident due to thrombus of basilar artery (disorder) 1.0
SNOMEDCT 195185009 Cerebral infarct due to thrombosis of precerebral arteries 1.0
SNOMEDCT 195186005 Cerebral infarction due to embolism of precerebral arteries 1.0
SNOMEDCT 195211003 Posterior cerebral artery syndrome 1.0
SNOMEDCT 230691006 CVA - cerebrovascular accident due to cerebral artery occlusion 1.0
SNOMEDCT 195190007 Cerebral infarction due to embolism of cerebral arteries 1.0
SNOMEDCT 195200006 Carotid artery syndrome hemispheric 1.0
SNOMEDCT 90099008 Subcortical leukoencephalopathy (disorder) 1.0
SNOMEDCT 276222004 Top of basilar syndrome (disorder) 1.0
SNOMEDCT 413758000 Cardioembolic stroke (disorder) 1.0
SNOMEDCT 195201005 Multiple and bilateral precerebral artery syndromes 1.0
SNOMEDCT 195209007 Middle cerebral artery syndrome 1.0
SNOMEDCT 16000511000119100 Cerebrovascular accident due to occlusion of left middle cerebral artery (disorder) 1.0
SNOMEDCT 16002031000119100 Cerebrovascular accident due to thrombus of right middle cerebral artery (disorder) 1.0
SNOMEDCT 230693009 Anterior cerebral circulation infarction (disorder) 1.0
SNOMEDCT 230696001 Posterior cerebral circulation infarction (disorder) 1.0
SNOMEDCT 24654003 Weber-Gubler syndrome (disorder) 1.0
SNOMEDCT 25133001 Completed stroke (disorder) 1.0
SNOMEDCT 195213000 Cerebellar stroke syndrome (disorder) 1.0
SNOMEDCT 276219001 Occipital cerebral infarction (disorder) 1.0
SNOMEDCT 276220007 Foville syndrome (disorder) 1.0
SNOMEDCT 276221006 Millard-Gubler syndrome (disorder) 1.0
SNOMEDCT 230701008 Pure sensorimotor lacunar infarction (disorder) 1.0
SNOMEDCT 307363008 Multiple lacunar infarcts (disorder) 1.0
SNOMEDCT 230702001 Lacunar ataxic hemiparesis (disorder) 1.0
SNOMEDCT 230703006 Dysarthria-clumsy hand syndrome (disorder) 1.0
SNOMEDCT 1089421000000100 Cerebral infarction due to stenosis of cerebral artery (disorder) 1.0
SNOMEDCT 230700009 Pure sensory lacunar infarction 1.0
SNOMEDCT 307766002 Left sided cerebral infarction 1.0
SNOMEDCT 125081000119106 Cerebral infarction due to occlusion of precerebral artery 1.0
SNOMEDCT 140921000119102 Ischaemic stroke without coma 1.0
SNOMEDCT 426107000 Acute lacunar infarction (disorder) 1.0
SNOMEDCT 734384004 Thrombosis of right middle cerebral artery (disorder) 1.0
SNOMEDCT 78569004 Posterior inferior cerebellar artery syndrome 1.0
SNOMEDCT 371041009 Embolic stroke (disorder) 1.0
SNOMEDCT 734383005 Thrombosis of left middle cerebral artery (disorder) 1.0
SNOMEDCT 71444005 Cerebral thrombosis 1.0
SNOMEDCT 75543006 Cerebral embolism 1.0

England hospitalization EHR: Ischaemic stroke

terminology code term code_type
ICD10 I63.9 Cerebral infarction, unspecified 1.0
ICD10 I63 Cerebral infarction 1.0
ICD10 I63.0 Cerebral infarction due to thrombosis of precerebral arteries 1.0
ICD10 I63.1 Cerebral infarction due to embolism of precerebral arteries 1.0
ICD10 I63.4 Cerebral infarction due to embolism of cerebral arteries 1.0
ICD10 I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries 1.0
ICD10 I63.8 Other cerebral infarction 1.0
ICD10 I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries 1.0
ICD10 I63.3 Cerebral infarction due to thrombosis of cerebral arteries 1.0

England primary care EHR: Stroke not otherwise specified

terminology code term code_type
SNOMEDCT 195212005 Brainstem stroke syndrome 1.0
SNOMEDCT 195213000 Cerebellar stroke syndrome 1.0
SNOMEDCT 195216008 Left sided cerebral hemisphere cerebrovascular accident 1.0
SNOMEDCT 195217004 Right sided CVA 1.0
SNOMEDCT 230690007 CVA - Cerebrovascular accident 1.0
SNOMEDCT 275434003 Stroke in the puerperium 1.0
SNOMEDCT 16371781000119100 Cerebellar stroke (disorder) 1.0
SNOMEDCT 195209007 Middle cerebral artery syndrome (disorder) 1.0
SNOMEDCT 195210002 Anterior cerebral artery syndrome (disorder) 1.0
SNOMEDCT 195211003 Posterior cerebral artery syndrome (disorder) 1.0
SNOMEDCT 195212005 Brainstem stroke syndrome (disorder) 1.0
SNOMEDCT 195216008 Left sided cerebral hemisphere cerebrovascular accident (disorder) 1.0
SNOMEDCT 195217004 Right sided cerebral hemisphere cerebrovascular accident (disorder) 1.0
SNOMEDCT 230706003 Hemorrhagic cerebral infarction (disorder) 1.0
SNOMEDCT 230708002 Posterior cerebral circulation hemorrhagic infarction (disorder) 1.0
SNOMEDCT 281240008 Extension of cerebrovascular accident (disorder) 1.0
SNOMEDCT 297138001 Embolus of circle of Willis (disorder) 1.0
SNOMEDCT 444172003 Recurrent transient cerebral ischemic attack (disorder) 1.0
SNOMEDCT 230690007 Cerebrovascular accident (disorder) 1.0
SNOMEDCT 230707007 Anterior cerebral circulation hemorrhagic infarction (disorder) 1.0
SNOMEDCT 230713003 Stroke of uncertain pathology (disorder) 1.0
SNOMEDCT 230714009 Anterior circulation stroke of uncertain pathology (disorder) 1.0
SNOMEDCT 230715005 Posterior circulation stroke of uncertain pathology (disorder) 1.0
SNOMEDCT 275434003 Stroke in the puerperium (disorder) 1.0

England hospitalization EHR: Stroke not otherwise specified

terminology code term code_type
ICD10 I64 Stroke, not specified as haemorrhage or infarction 1.0

England hospitalization EHR: Subarachnoid hemorrhage

terminology code term code_type
ICD10 I60 Nontraumatic subarachnoid hemorrhage 1.0

England primary care EHR: Transient ischaemic attack

terminology code term code_type
SNOMEDCT 195206000 Intermittent cerebral ischaemia 1.0
SNOMEDCT 230716006 Anterior circulation transient ischaemic attack 1.0
SNOMEDCT 266257000 TIA 1.0
SNOMEDCT 15258001 Subclavian steal syndrome (disorder) 1.0
SNOMEDCT 195199008 Vertebrobasilar artery syndrome (disorder) 1.0
SNOMEDCT 195205001 Impending cerebral ischemia (disorder) 1.0
SNOMEDCT 34781003 Vertebral artery syndrome (disorder) 1.0
SNOMEDCT 64009001 Basilar artery syndrome (disorder) 1.0
SNOMEDCT 751371000000107 Personal history of transient ischaemic attack (situation) 1.0
SNOMEDCT 230717002 Vertebrobasilar territory transient ischemic attack (disorder) 1.0

England hospitalization EHR: Transient ischaemic attack

terminology code term code_type
ICD10 G45.0 Vertebro-basilar artery syndrome 1.0
ICD10 G45.1 Carotid artery syndrome (hemispheric) 1.0
ICD10 G45.2 Multiple and bilateral precerebral artery syndromes 1.0
ICD10 G45.3 Amaurosis fugax 1.0
ICD10 G45.4 Transient global amnesia 1.0
ICD10 G45.8 Other transient cerebral ischaemic attacks and related syndromes 1.0
ICD10 G45.9 Transient cerebral ischaemic attack, unspecified 1.0
ICD10 G46.0 Middle cerebral artery syndrome"" 1.0
ICD10 G46.1 Anterior cerebral artery syndrome"" 1.0
ICD10 G46.2 Posterior cerebral artery syndrome"" 1.0
ICD10 I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction 1.0
ICD10 I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction 1.0

Publication

Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, and thrombocytopenic events: whole population cohort study in 46 million adults in England

CVD-COVID-UK consortium, William N Whiteley, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Venexia Walker, Rachel Denholm, Ashley Akbari, Efosa Omigie, Sam Hollings, Emanuele Di Angelantonio, Spiros Denaxas, Angela Wood, Jonathan A C Sterne, Cathie Sudlow

medRxiv 2021.08.18.21262222; doi: https://doi.org/10.1101/2021.08.18.21262222