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Chronic Kidney Disease
Metadata
Name | Chronic Kidney Disease |
Type | Disease or Syndrome |
Group | Genitourinary |
Data Sources |
|
Clinical Terminologies | |
Codelists | |
Valid Event Data Range | 01/01/1999 - 01/07/2016 |
Sex |
Female Male |
Authors | Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A |
Agreement Date | 20 May 2019 |
Version (UUID) | 1 (g6TjPwLiMqVwz7YtFMa8eQ) |
Implementation
Apply modified CALIBER 'Chronic Kidney Disease' algorithm in CPRD primary care data as follows: A patient is defined as having had CKD stage 3 or above at a specified date: IF egfr_ckdepi recorded on or before specified date, THEN IF egfr_ckdepi <60 ml/min on the most recent date (index date) before the specified date AND IF egfr_ckdepi <60 ml/min on any date greater than 90 days BEFORE the index date above THEN classify as having CKD3 or above ELSE the patient is not defined as having CKD stage 3 or above. Where egfr_ckdepi up to and including 31 Dec 2013 is defined as: egfr_ckdepi = 141 * min(crea_gprd * 0.010746 / K, 1)^alpha * max(crea_gprd * 0.010746 / K, 1)^-1.209 * 0.993^age * 1.018 [if female] * 1.159 [if black] where: alpha = -0.329 for females, -0.411 for males K = 0.7 for females, 0.9 for males Where egfr_ckdepi from and including 1 Jan 2014 is defined as: egfr_ckdepi = 141 * min(crea_gprd * 0.010746 / K, 1)^alpha * max(crea_gprd * 0.0.011312/ K, 1)^-1.209 * 0.993^age * 1.018 [if female] * 1.159 [if black] where: alpha = -0.329 for females, -0.411 for males K = 0.7 for females, 0.9 for males Where crea_gprd is defined as: IF enttype = 165 [Serum creatinine] AND data1 [Operator] = 3 ["="] AND data2 [Value] > 0 THEN crea_gprd = data2
Publications
Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3