Metadata

Name Down's syndrome
Type Disease or Syndrome
Group Perinatal
Data Sources

Clinical Terminologies Read Version 2
ICD-10
Codelists
Valid Event Data Range 01/01/1999 - 01/07/2016
Sex Female
Male
Authors Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A
Agreement Date 20 May 2019
Version (UUID) 1 (eJfgxZ6gX5nEXWCoXzQ3KK)

Primary care

Disease Readcode Medcode ReadcodeDescr Category
Down's syndrome PJ00.00 42701.0 Trisomy 21, meiotic nondisjunction Diagnosis of Down's syndrome
Down's syndrome PJ01.00 32010.0 Trisomy 21, mosaicism Diagnosis of Down's syndrome
Down's syndrome PJ01.11 107919.0 Trisomy 21, mitotic nondisjunction Diagnosis of Down's syndrome
Down's syndrome PJ02.00 61499.0 Trisomy 21, translocation Diagnosis of Down's syndrome
Down's syndrome PJ02.11 101309.0 Partial trisomy 21 in Down's syndrome Diagnosis of Down's syndrome
Down's syndrome PJ0..00 1543.0 Down's syndrome - trisomy 21 Diagnosis of Down's syndrome
Down's syndrome PJ0..11 23489.0 Mongolism Diagnosis of Down's syndrome
Down's syndrome PJ0..12 18415.0 Trisomy 21 Diagnosis of Down's syndrome
Down's syndrome PJ0z.00 10759.0 Down's syndrome NOS Diagnosis of Down's syndrome
Down's syndrome PJ0z.11 61627.0 Trisomy 21 NOS Diagnosis of Down's syndrome

Secondary care

Diagnoses

Disease ICD10code ICD10codeDescr Category
Down's syndrome Q90 Down's syndrome Diagnosis of Down's syndrome

Implementation

At the specified date, a patient is defined as having had Down's syndrome IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

Primary care
1. Down's syndrome diagnosis or history of diagnosis during a consultation 
OR
Secondary care (ICD10)
1. ALL diagnoses of Down's syndrome or history of diagnosis during a hospitalization

Publications

Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3