Metadata

Name Sickle-cell anaemia
Type Disease or Syndrome
Group Haematological or immunological
Data Sources

Clinical Terminologies Read Version 2
ICD-10
Codelists kuan_sickle_cell_BoyuDsY7sCnGANEAFw9ffb_Read2.csv kuan_sickle_cell_BoyuDsY7sCnGANEAFw9ffb_ICD10.csv
Valid Event Data Range 01/01/1999 - 01/07/2016
Sex Female
Male
Authors Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A
Agreement Date 20 May 2019
Version (UUID) 1 (BoyuDsY7sCnGANEAFw9ffb)

Primary care

Disease Readcode Medcode ReadcodeDescr Category
Sickle-cell anaemia 1458.00 100001.0 History of sickle cell anaemia History of Sickle-cell anaemia
Sickle-cell anaemia D104211 31075.0 Sickle-cell thalassaemia Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D106000 69964.0 Sickle-cell anaemia of unspecified type Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D106100 32937.0 Sickle-cell anaemia with no crisis Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D106200 31370.0 Sickle-cell anaemia with crisis Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D106300 31306.0 Sickle-cell anaemia with haemoglobin C disease Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D106400 8119.0 Sickle-cell anaemia with haemoglobin D disease Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D106500 93872.0 Sickle-cell anaemia with haemoglobin E disease Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D106.00 23519.0 Sickle-cell anaemia Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D106z00 57397.0 Sickle-cell anaemia NOS Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia Dyu1200 48295.0 [X]Other sickle-cell disorders Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia F422100 11874.0 Proliferative retinopathy due to sickle cell disease History of Sickle-cell anaemia
Sickle-cell anaemia K0G..00 107027.0 Sickle cell nephropathy History of Sickle-cell anaemia

Secondary care

Diagnoses

Disease ICD10code ICD10codeDescr Category
Sickle-cell anaemia D57.0 Sickle-cell anaemia with crisis Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D57.1 Sickle-cell anaemia without crisis Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D57.2 Double heterozygous sickling disorders Diagnosis of Sickle-cell anaemia
Sickle-cell anaemia D57.8 Other sickle-cell disorders Diagnosis of Sickle-cell anaemia

Implementation

At the specified date, a patient is defined as having had Sickle-cell anaemia IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

Primary care
1. Sickle-cell anaemia diagnosis or history of diagnosis during a consultation 
OR
Secondary care (ICD10)
1. ALL diagnoses of Sickle-cell anaemia or history of diagnosis during a hospitalization

Publications

Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3