Metadata

Name Hypo or hyperthyroidism
Type Disease or Syndrome
Group Endocrine
Data Sources

Clinical Terminologies Read Version 2
ICD-10
Codelists kuan_thyroid_FgVJooWzCgt2V9UnTYdU5S_Read2.csv kuan_thyroid_FgVJooWzCgt2V9UnTYdU5S_ICD10.csv
Valid Event Data Range 01/01/1999 - 01/07/2016
Sex Female
Male
Authors Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A
Agreement Date 20 May 2019
Version (UUID) 1 (FgVJooWzCgt2V9UnTYdU5S)

Primary care

Disease Readcode Medcode ReadcodeDescr Category
Hypo or hyperthyroidism 1431.00 6245.0 H/O: hyperthyroidism History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 1431.11 8038.0 H/O: thyrotoxicosis History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 143..11 4937.0 H/O: thyroid disorder History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 1432.00 3611.0 H/O: hypothyroidism History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 1433.00 35608.0 H/O: thyroid disorder NOS History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 212P.00 26362.0 Hyperthyroidism resolved History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 66B4.00 28530.0 Thyroid eye disease History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 66B..00 8268.0 Thyroid disease monitoring History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 66BB.00 95885.0 Hypothyroidism annual review History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 66BZ.00 28822.0 Thyroid disease monitoring NOS History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 8CR5.00 85955.0 Hypothyroidism clinical management plan History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 9Oj0.00 46057.0 Hypothyroidism monitoring first letter History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 9Oj1.00 46630.0 Hypothyroidism monitoring second letter History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 9Oj2.00 46640.0 Hypothyroidism monitoring third letter History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 9Oj3.00 19367.0 Hypothyroidism monitoring verbal invite History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 9Oj4.00 85661.0 Hypothyroidism monitoring telephone invitation History of Hypo or hyperthyroidism
Hypo or hyperthyroidism 9Oj..00 28735.0 Hypothyroidism monitoring administration History of Hypo or hyperthyroidism
Hypo or hyperthyroidism C020000 26702.0 Toxic diffuse goitre with no crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C020100 57011.0 Toxic diffuse goitre with crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C020200 100476.0 Thyroid-associated dermopathy Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C020.00 23315.0 Toxic diffuse goitre Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C020.11 44405.0 Basedow's disease Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C020.12 5257.0 Graves' disease Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C020z00 49334.0 Toxic diffuse goitre NOS Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C021000 26869.0 Toxic uninodular goitre with no crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C021.00 53280.0 Toxic uninodular goitre Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C021z00 61498.0 Toxic uninodular goitre NOS Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C022000 46985.0 Toxic multinodular goitre with no crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C022.00 11426.0 Toxic multinodular goitre Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C022z00 53981.0 Toxic multinodular goitre NOS Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C023000 68512.0 Toxic nodular goitre unspecified with no crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C023100 100004.0 Toxic nodular goitre unspecified with crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C023.00 15790.0 Toxic nodular goitre unspecified Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C023z00 49361.0 Toxic nodular goitre NOS Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02..00 677.0 Thyrotoxicosis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02..11 1472.0 Hyperthyroidism Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02..12 10760.0 Toxic goitre Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02y000 51273.0 Thyrotoxicosis of other specified origin with no crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02y100 106532.0 Thyrotoxicosis of other specified origin with crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02y300 19205.0 Thyroid crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02y.00 43136.0 Thyrotoxicosis of other specified origin Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02yz00 34220.0 Thyrotoxicosis of other specified origin NOS Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02z000 26701.0 Thyrotoxicosis without mention of goitre or cause no crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02z100 3194.0 Thyrotoxicosis without mention of goitre, cause with crisis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02z.00 15565.0 Thyrotoxicosis without mention of goitre or other cause Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C02zz00 26699.0 Thyrotoxicosis NOS Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C040.00 28852.0 Postsurgical hypothyroidism History of Hypo or hyperthyroidism
Hypo or hyperthyroidism C040.11 47521.0 Post ablative hypothyroidism History of Hypo or hyperthyroidism
Hypo or hyperthyroidism C041000 11322.0 Irradiation hypothyroidism History of Hypo or hyperthyroidism
Hypo or hyperthyroidism C041.00 50275.0 Other postablative hypothyroidism History of Hypo or hyperthyroidism
Hypo or hyperthyroidism C041z00 51706.0 Postablative hypothyroidism NOS History of Hypo or hyperthyroidism
Hypo or hyperthyroidism C043.00 25913.0 Other iatrogenic hypothyroidism History of Hypo or hyperthyroidism
Hypo or hyperthyroidism C043z00 38976.0 Iatrogenic hypothyroidism NOS History of Hypo or hyperthyroidism
Hypo or hyperthyroidism C046.00 31971.0 Autoimmune myxoedema Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04..00 3290.0 Acquired hypothyroidism Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04..11 1619.0 Myxoedema Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04..12 14704.0 Thyroid deficiency Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04..13 273.0 Hypothyroidism Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04y.00 24748.0 Other acquired hypothyroidism Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04z000 56722.0 Premature puberty due to hypothyroidism Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04z100 59702.0 Myxoedema coma Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04z.00 3941.0 Hypothyroidism NOS Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04z.11 20310.0 Pretibial myxoedema - hypothyroid Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04z.12 23014.0 Thyroid insufficiency Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C04z.13 18282.0 Hypothyroid goitre, acquired Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C052.00 26833.0 Chronic lymphocytic thyroiditis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C052.11 3857.0 Autoimmune thyroiditis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C052.12 3436.0 Hashimoto's disease Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C053.00 70244.0 Chronic fibrous thyroiditis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C05..00 1346.0 Thyroiditis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C05y400 65907.0 Chronic thyroiditis with transient thyrotoxicosis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C05y.00 65444.0 Other and unspecified chronic thyroiditis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C05z.00 20909.0 Thyroiditis NOS Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C06y100 69113.0 Thyroid atrophy Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism C134300 11146.0 TSH - thyroid-stimulating hormone deficiency Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism Cyu1100 73107.0 [X]Other sp cified hypothyroidism Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism Cyu1300 72690.0 [X]Other thyrotoxicosis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism Cyu1400 95335.0 [X]Other chronic thyroiditis Diagnosis of Hypo or Hyperthyroidism
Hypo or hyperthyroidism F11x500 47658.0 Cerebral degeneration due to myxoedema History of Hypo or hyperthyroidism
Hypo or hyperthyroidism F381400 61069.0 Myasthenic syndrome due to hypothyroidism History of Hypo or hyperthyroidism
Hypo or hyperthyroidism F381600 47695.0 Myasthenic syndrome due to thyrotoxicosis History of Hypo or hyperthyroidism
Hypo or hyperthyroidism F395300 51416.0 Myopathy due to myxoedema History of Hypo or hyperthyroidism
Hypo or hyperthyroidism F395400 48167.0 Myopathy due to thyrotoxicosis History of Hypo or hyperthyroidism
Hypo or hyperthyroidism F4G2000 1567.0 Thyrotoxic exophthalmos History of Hypo or hyperthyroidism
Hypo or hyperthyroidism FyuBD00 68626.0 [X]Dysthyroid exophthalmos History of Hypo or hyperthyroidism
Hypo or hyperthyroidism G557500 20035.0 Thyrotoxic heart disease History of Hypo or hyperthyroidism

Secondary care

Diagnoses

Disease ICD10code ICD10codeDescr Category
Hypo or hyperthyroidism E03.5 Myxoedema coma Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E03.8 Other specified hypothyroidism Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E03.9 Hypothyroidism, unspecified Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E05.0 Thyrotoxicosis with diffuse goitre Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E05.1 Thyrotoxicosis with toxic single thyroid nodule Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E05.2 Thyrotoxicosis with toxic multinodular goitre Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E05.5 Thyroid crisis or storm Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E05.8 Other thyrotoxicosis Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E05.9 Thyrotoxicosis, unspecified Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E06.2 Chronic thyroiditis with transient thyrotoxicosis Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E06.3 Autoimmune thyroiditis Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E06.5 Other chronic thyroiditis Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism E06.9 Thyroiditis, unspecified Diagnosis of Hypo or hyperthyroidism
Hypo or hyperthyroidism H06.2 Dysthyroid exophthalmos Diagnosis of Hypo or hyperthyroidism

Implementation

At the specified date, a patient is defined as having had Hypo or hyperthyroidism IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

Primary care
1. Hypo or hyperthyroidism diagnosis or history of diagnosis during a consultation 
OR
Secondary care (ICD10)
1. ALL diagnoses of Hypo or hyperthyroidism or history of diagnosis during a hospitalization

Publications

Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3